產(chǎn)品編號(hào) | bsm-61098R |
英文名稱 | CD24 Recombinant Rabbit mAb |
中文名稱 | CD24重組兔單抗 |
別 名 | CD24; CD24 antigen; CD24A; HAS; Signal transducer CD24. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 8 kDa |
檢測(cè)分子量 | 31-45 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human CD24 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. SWISS: P25063 Gene ID: 100133941 神經(jīng)干細(xì)胞標(biāo)志物 腫瘤標(biāo)志物 CD24是一種低分子質(zhì)量高度糖基化的黏附分子, 主要表達(dá)在造血系統(tǒng). 最近研究表明, 在造血系統(tǒng)腫瘤和一些器官的實(shí)體瘤表面可見(jiàn)CD24高表達(dá)。 近幾年很多學(xué)者認(rèn)為:CD24在前列腺癌、非小細(xì)胞肺癌、鼻咽癌、原發(fā)性肝細(xì)胞癌、膽管細(xì)胞癌、麥克爾細(xì)胞癌、神經(jīng)源性腫瘤、胰腺癌、胃癌、結(jié)腸癌、腎細(xì)胞癌、B細(xì)胞淋巴瘤、乳腺癌等腫瘤組織中表達(dá)增強(qiáng), 且和腫瘤侵襲轉(zhuǎn)移、復(fù)發(fā)和預(yù)后相關(guān)。 |
產(chǎn)品圖片 | |