產品編號 | bsm-61101R |
英文名稱 | Caveolin-2 Recombinant Rabbit mAb |
中文名稱 | 細胞質膜微囊蛋白-2重組兔單抗 |
別 名 | CAV2; Caveolae protein 20 Kd; Caveolin 2; Caveolin 2 isoform a and b; Caveolin-2. |
抗體來源 | Rabbit |
克隆類型 | Recombinant |
交叉反應 | Human |
產品應用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 18 kDa |
檢測分子量 | 18 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human Caveolin 2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產品介紹 |
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. SWISS: P51636 Gene ID: 858 Caveolin是細胞生長相關信號途徑及腫瘤發(fā)生發(fā)展過程中重要的抑制因子,Caveolae是細胞膜內的特殊膜結構,參與包括細胞的分子運輸、細胞粘附和信號轉導在內的多種細胞活動。Caveolin-1是Caveolae中重要的結構蛋白,抑制細胞生長,與多種人類腫瘤發(fā)生發(fā)展相關的信號分子相互作用。Caveolin在信號轉導的整合中起支架蛋白的作用。Caveolin構成了一個蛋白家族,他們是細胞質膜中發(fā)夾樣結構域的主要結構成分。Caveolin在信號轉導的整合中起支架蛋白的作用。至今已經鑒定了3種Caveolin |
產品圖片 | |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |