產(chǎn)品編號(hào) | bsm-61114R |
英文名稱 | Adiponectin Recombinant Rabbit mAb |
中文名稱 | 脂聯(lián)素重組兔單抗 |
別 名 | 30 kDa adipocyte complement related protein; ACDC; ACRP30; Adipocyte; Adiponectin; Adipoq; Adipose most abundant gene transcript 1; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM1; GBP28; Gelatin binding protein; Gelatin binding protein 28. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 26 kDa |
檢測(cè)分子量 | 30 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human Adiponectin |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. SWISS: Q15848 Gene ID: 9370 脂聯(lián)素又被稱作Acrp30、apM1、AdipoQ、GBP28。 最初, 脂聯(lián)素是在人體皮下脂肪組織、血漿和鼠科動(dòng)物的脂肪細(xì)胞中被發(fā)現(xiàn)人體內(nèi)的脂聯(lián)素由244個(gè)氨基酸組成,分子量為27KD。 脂聯(lián)素影響脂肪和糖類的代謝,還可以降低多種粘附分子(VCAM-1、ICAM-1、選擇素-E) 在內(nèi)皮細(xì)胞的表達(dá)。并影響著腫瘤壞死因子(TNF)分泌,近年來(lái)主要用于糖尿病的研究。 脂聯(lián)素作為一種胰島素超敏化激素(An Insulin–sensitizing Hormone),可以增加促進(jìn)骨骼肌細(xì)胞的脂肪酸氧化和糖吸收,明 |
產(chǎn)品圖片 | |