| 產(chǎn)品編號 | bs-1924R |
| 英文名稱 | GPAT4 Rabbit pAb |
| 中文名稱 | 甘油-3-磷酸?；D(zhuǎn)移酶4抗體 |
| 別 名 | GPAT4_HUMAN; Glycerol-3-phosphate acyltransferase 4; AGPAT6; TSARG7; UNQ551/PRO1108; EC:2.3.1.15; 1-acylglycerol-3-phosphate O-acyltransferase 6(1-AGP acyltransferase 6; 1-AGPAT 6); Acyl-CoA:glycerol-3-phosphate acyltransferase 4; Lysophosphatidic acid acyltransferase zeta(LPAAT-zeta); Testis spermatogenesis apoptosis-related protein 7; LPAAT-δ; |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 細(xì)胞凋亡 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPAT4: 351-456/456 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
AGPAT6 is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland. It converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Function: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long-chain fatty acyl-CoAs. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Ubiquitous. Relatively high level of expression in skeletal muscle, heart and testis. Relatively low level of expression in lung. Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. SWISS: Q86UL3 Gene ID: 137964 Database links: Entrez Gene: 137964 Human Entrez Gene: 102247 Mouse SwissProt: Q86UL3 Human SwissProt: Q8K2C8 Mouse Unigene: 355753 Human Unigene: 200898 Mouse |
