| 產(chǎn)品編號(hào) | bs-3677R |
| 英文名稱 | CYP8A1 Rabbit pAb |
| 中文名稱 | 前列環(huán)素合成酶抗體 |
| 別 名 | PTGI; PTGIS; CYP8; Cytochrome P450, family 8, subfamily A, polypeptide 1; EC 5.3.99.4; MGC126858; MGC126860; OTTHUMP00000031777; PGIS; Prostacyclin synthase; Prostaglandin I2(prostacyclin) synthase; Prostaglandin I2 synthase; PTGIS_HUMAN. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 免疫學(xué) 糖尿病 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 55 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS: 401-500/500 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Tissue Specificity: Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate. Similarity: Belongs to the cytochrome P450 family. SWISS: Q16647 Gene ID: 5740 Database links: Entrez Gene: 5740 Human Entrez Gene: 19223 Mouse Omim: 601699 Human SwissProt: Q16647 Human SwissProt: O35074 Mouse Unigene: 5247 Cow Unigene: 302085 Human Unigene: 2339 Mouse Unigene: 73051 Rat |
