| 產(chǎn)品編號 | bs-3803R |
| 英文名稱 | Rabbit Anti-Mammaglobin B antibody |
| 中文名稱 | 乳腺珠蛋白2抗體 |
| 別 名 | Lipophilin C; LPHC; Mammaglobin 2; MGB2; MGC71973; SCGB2A1; Secretoglobin, family 2A, member 1; UGB3. |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 結(jié)合蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Rat,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 8.5kDa |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Mammaglobin B: 41-95/95 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammaglobin B may bind androgens and other steroids, it may also bind estramustine, a chemotherapeutic agent used for prostate cancer. It may be under transcriptional regulation of steroid hormones. Subunit: Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head. Tissue Specificity: Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. SWISS: O75556 Gene ID: 4246 乳腺球蛋白是一個乳腺相關(guān)糖蛋白，它是一個分泌素家族（包括子宮球蛋白和lipophilin）成員的遠親。與其他分泌素家族成員不同，乳腺球蛋白的mRNA在乳腺組織中特異表達。在石蠟組織切片的檢測中，該抗體檢測乳腺癌組織中的乳腺珠蛋白敏感度高達80%。當(dāng)和其他乳腺特異標(biāo)記如GCDFP-15聯(lián)合應(yīng)用時，檢測乳腺珠蛋白敏感度高達84%。有資料表明檢測乳腺球蛋白，在鑒定原發(fā)癌是否發(fā)生轉(zhuǎn)移中起到至關(guān)重要的作用。 |
