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Cytokeratin 3+12 Rabbit pAb (bs-2369R)  
訂購熱線:400-901-9800
訂購郵箱:[email protected]
訂購QQ:  400-901-9800
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-2369R
英文名稱 Cytokeratin 3+12 Rabbit pAb
中文名稱 細胞角蛋白3+12抗體
別    名 CK 12; CK 3; CK12; CK3; Cytokeratin 12; Cytokeratin 3; K12; K3; keratin 12(Meesmann corneal dystrophy); Keratin 12; Keratin 3; Keratin, type I cytoskeletal 12; Keratin, type II cytoskeletal 3; KRT12; KRT3; 65 kDa cytokeratin.  
Specific References  (1)     |     bs-2369R has been referenced in 1 publications.
[IF=3.231] Xu W et al. An in situ hydrogel based on carboxymethyl chitosan and sodium alginate dialdehyde for corneal wound healing after alkali burn.(2018) J Biomed Mater Res A.  IHF ;  Rabbit.  
研究領域 腫瘤  細胞生物  免疫學  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65+54 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 細胞外基質(zhì) 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cytokeratin 3+12 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cytokeratin 3 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

SWISS:
P12035

Gene ID:
3850

Database links:

Entrez Gene: 3850 Human

Omim: 148043 Human

SwissProt: P12035 Human

Unigene: 680652 Human



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