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phospho-CTNNBIP1 (Thr43+Ser50) Rabbit pAb (bs-5266R)  
訂購熱線:400-901-9800
訂購郵箱:[email protected]
訂購QQ:  400-901-9800
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-5266R
英文名稱 phospho-CTNNBIP1 (Thr43+Ser50) Rabbit pAb
中文名稱 磷酸化β鏈接素相互作用蛋白1抗體
別    名 beta catenin interacting protein 1; beta catenin interacting protein ICAT; Catenin beta interacting protein 1; CTNNBIP 1; ICAT; Inhibitor of beta catenin and Tcf 4; MGC15093; CNBP1_HUMAN.  
產品類型 磷酸化抗體 
研究領域 細胞生物  免疫學  信號轉導  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse,Rabbit,Cow,Chicken)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 9 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CTNNBIP1 around the phosphorylation site of Thr43/Ser50: LR(p-T)YAGVVN(p-S)QL 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 CTNNBIP1 (Catenin, beta interacting protein 1) binds to beta-catenin and prevents the interaction between beta-catenin and TCF transcription factor family members. It is a negative regulator of the Wnt signaling pathway.

Function:
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

Subunit:
Binds CTNNB1.

Subcellular Location:
Cytoplasm (By similarity). Nucleus (By similarity).

Similarity:
Belongs to the CTNNBIP1 family.

SWISS:
Q9NSA3

Gene ID:
56998

Database links:

Entrez Gene: 56998 Human

Entrez Gene: 67087 Mouse

Entrez Gene: 503000 Rat

Omim: 607758 Human

SwissProt: Q9NSA3 Human

SwissProt: Q9JJN6 Mouse

Unigene: 463759 Human

Unigene: 299735 Mouse

Unigene: 162132 Rat

 



產品圖片
Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-phospho-CTNNBIP1(Thr43+Ser50) Polyclonal Antibody, Unconjugated(bs-5266R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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