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Rabbit Anti-phospho-KCNC1 (Ser503)  antibody (bs-5403R)  
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產(chǎn)品編號 bs-5403R
英文名稱 Rabbit Anti-phospho-KCNC1 (Ser503)  antibody
中文名稱 磷酸化離子通道蛋白Kv3.1抗體
別    名 KCNC1 (phospho S503); p-KCNC1 (phospho Ser503); C230009H10Rik; FLJ41162; FLJ42249; FLJ43491; Kcr2 1; KShIIIB; Kv3.1; Kv4; MGC129855; NGK2; Potassium voltage-gated channel subfamily C member 1; Shaw; Voltage gated potassium channel; KCNC1_RAT; Voltage gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv3.1; KCNC1_RAT.  
Specific References  (1)     |     bs-5403R has been referenced in 1 publications.
[IF=4.636] Cheng Wanpeng. et al. Transcriptomic analysis reveals the effects of maternal selenium deficiency on placental transport, hormone synthesis, and immune response in mice. METALLOMICS. 2022 Aug;:  WB ;  Mouse.  
產(chǎn)品類型 磷酸化抗體 
研究領域 細胞生物  免疫學  神經(jīng)生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat KCNC1 around the phosphorylation site of Ser503: AD(p-S)KL 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.

Function:
This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Subunit:
Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

SWISS:
P25122

Gene ID:
25327

Database links:

Entrez Gene: 3746 Human

Entrez Gene: 16502 Mouse

Entrez Gene: 25327 Rat

Omim: 176258 Human

SwissProt: P48547 Human

SwissProt: P15388 Mouse

SwissProt: P25122 Rat

Unigene: 303870 Human

Unigene: 552896 Human

Unigene: 249386 Mouse

Unigene: 33095 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kDa Observed band size: 53 kDa
Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
Sample: HL60(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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