| 產(chǎn)品編號(hào) | bs-6825R |
| 英文名稱 | Rabbit Anti-MAGEB6 antibody |
| 中文名稱 | 黑色素瘤相關(guān)抗原B6抗體 |
| 別 名 | Cancer/testis antigen 3.4; CT3.4; MAGEB6 antigen; Melanoma associated antigen B6; MAGB6_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞類型標(biāo)志物 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 44kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGEB6: 151-250/407 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different type of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown. MAGE-B6 is expressed in testis and tumors of various histological origins but has not been shown to be expressed in other normal tissues. Tissue Specificity: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins. Similarity: Contains 1 MAGE domain. SWISS: Q8N7X4 Gene ID: 158809 Database links: Entrez Gene: 158809 Human Omim: 300467 Human SwissProt: Q8N7X4 Human |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (human melanoma tumor); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAGEB6) Polyclonal Antibody, Unconjugated (bs-6825R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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