国产成人福利久久久_2019色 亚洲 日韩 国产 在线_免费在线观看黄色视频亚洲不卡_综合自拍三级欧美_久久精品高清最新地址无码_成人网站在线下载_精品电影日韩亚洲_麻豆影院无码一级_欲妇的爆乳大肉臀小说_在线看亚洲十八禁网

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
完结小说,已完本玄幻小说排行榜,怎么写网络小说
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
HIPK4 Rabbit pAb (bs-7612R)  
訂購熱線:400-901-9800
訂購郵箱:[email protected]
訂購QQ:  400-901-9800
技術支持:[email protected]
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-7612R
英文名稱 HIPK4 Rabbit pAb
中文名稱 同源相互作用蛋白激酶4抗體
別    名 HIPK 4; HIPK4; HIPK4_HUMAN; Homeodomain interacting protein kinase 4; Homeodomain-interacting protein kinase 4.  
研究領域 細胞生物  信號轉(zhuǎn)導  細胞凋亡  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 69 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HIPK4: 251-350/616 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. The homeodomain-interacting protein kinases (HIPK1, HIPK2, HIPK3 and HIPK4) comprise a subfamily of kinase proteins that have a conserved protein kinase domain, as well as a separate domain that interacts with homeoproteins. HIPK4 (Homeodomain-interacting protein kinase 4) is a 616 amino acid protein that localizes to the cytoplasm and exists as two isoforms that are produced by alternative splicing events. Like other members of the HIPK family, HIPK4 functions as a protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to act as a corepressor of target transcription factors.

Function:
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors.

Subcellular Location:
Cytoplasm (By similarity).

Post-translational modifications:
Autophosphorylated (By similarity).

Similarity:
Belongs to the protein kinase superfamily. CMGCSer/Thr protein kinase family. HIPK subfamily.
Contains 1 protein kinase domain.

SWISS:
Q8NE63

Gene ID:
147746

Database links:

Entrez Gene: 147746 Human

Entrez Gene: 233020 Mouse

Entrez Gene: 308449 Rat

Omim: 611712 Human

SwissProt: Q8NE63 Human

SwissProt: Q3V016 Mouse

SwissProt: Q4V793 Rat

Unigene: 79363 Human

Unigene: 429716 Mouse

Unigene: 41008 Rat



版權所有 2004-2026 ourmotor168.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號