| 產(chǎn)品編號(hào) | bs-7989R |
| 英文名稱 | Rabbit Anti-CCDC52 antibody |
| 中文名稱 | 卷曲螺旋結(jié)構(gòu)域蛋白52抗體 |
| 別 名 | Coiled coil domain containing protein 52; Coiled-coil domain-containing protein 52; FLJ26064; FLJ44949; SPICE_HUMAN; spice1; Spindle and centriole-associated protein 1; Spindle and centriole-associated protein. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞分化 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 96kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCDC52: 51-140/855 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The gene encoding CCDC52 (Coiled-coil domain-containing protein 52), a 855 amino acid protein, exists on human chromosome 3. Function: Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis. Subunit: Interacts with CEP120 Subcellular Location: Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. SWISS: Q8N0Z3 Gene ID: 152185 Database links: Entrez Gene: 152185 Human Omim: 613447 Human SwissProt: Q8N0Z3 Human Unigene: 477144 Human |
