| 產(chǎn)品編號 | bs-11891R |
| 英文名稱 | Rabbit Anti-Myotrophin antibody |
| 中文名稱 | 顆粒細胞分化蛋白抗體 |
| 別 名 | FLJ31098; FLJ99857; GCDP; Granule cell differentiation protein; MTPN; MTPN_HUMAN; Myotrophin; Protein V 1; Protein V-1; V 1; MTPN_HUMAN. |
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Specific References (1) | bs-11891R has been referenced in 1 publications.
[IF=2.379] Jieting Liu. et al. Identification of robust diagnostic and prognostic gene signatures in different grades of gliomas: a retrospective study. Peerj. 2021 May;9:e11350 WB ; Human.
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| 研究領(lǐng)域 | 心血管 細胞生物 神經(jīng)生物學(xué) 細胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 13kDa |
| 細胞定位 | 細胞核 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from humam Myotrophin/GCDP: 41-118/118 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008] Function: Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy. Subunit: Interacts with RELA (By similarity). Interacts with the heterodimer formed by CAPZA1 and CAPZB. Subcellular Location: Cytoplasm (Probable). Nucleus (By similarity). Cytoplasm, perinuclear region (By similarity). Tissue Specificity: Ubiquitous. Similarity: Belongs to the myotrophin family. Contains 3 ANK repeats. SWISS: P58546 Gene ID: 136319 Database links: Entrez Gene: 136319 Human Entrez Gene: 14489 Mouse Omim: 606484 Human SwissProt: P58546 Human SwissProt: P62774 Mouse SwissProt: Q7T2B9 Zebrafish Unigene: 602015 Human Unigene: 182746 Mouse Unigene: 3239 Rat Unigene: 75187 Zebrafish |
