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Rabbit Anti-BMP8b  antibody (bs-12873R)  
~~~促銷,代碼KT202502A~~~
~~~促銷,代碼KT202502B~~~
訂購熱線:400-901-9800
訂購郵箱:[email protected]
訂購QQ:  400-901-9800
技術(shù)支持:[email protected]
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-12873R
英文名稱 Rabbit Anti-BMP8b  antibody
中文名稱 骨形態(tài)發(fā)生蛋白8b抗體
別    名 BMP8B_HUMAN; Bone morphogenetic protein 8B; BMP-8B; BMP-8; Osteogenic protein 2 (OP-2); Osteogenic protein-2; OP2; OP 2; BMP8;   
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 16kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP8b: 311-402/402 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

Function:
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Similarity:
Belongs to the TGF-beta family.

SWISS:
P34820

Gene ID:
656

Database links:

Entrez Gene: 656 Human

Entrez Gene: 12164 Mouse

SwissProt: P34820 Human

SwissProt: P55105 Mouse



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