產(chǎn)品編號(hào) | bs-13559R |
英文名稱(chēng) | Rabbit Anti-Z DNA binding protein antibody |
中文名稱(chēng) | Z DNA結(jié)合蛋白抗體 |
別 名 | C20orf183; DAI; DLM 1; DLM1; DNA-dependent activator of interferon regulatory factors; DNA-dependent activator of IRFs; OTTHUMP00000031373; OTTHUMP00000174290; OTTHUMP00000237854; Tumor stroma and activated macrophage protein DLM 1; Tumor stroma and activated macrophage protein DLM-1; Z-DNA-binding protein 1; ZBP 1; Zbp1; ZBP1_HUMAN; ZDBP1. |
研究領(lǐng)域 | 細(xì)胞生物 結(jié)合蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 46kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Z DNA binding protein: 301-400/429 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Function: May play a role in host defense against tumors and pathogens. Binds Z-DNA. Tissue Specificity: Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. Expressed to a lesser extent in thymus, lung and liver. Similarity: Contains 2 DRADA repeats. SWISS: Q9H171 Gene ID: 81030 Database links: Entrez Gene: 81030 Human Entrez Gene: 58203 Mouse Omim: 606750 Human SwissProt: Q9H171 Human SwissProt: Q9QY24 Mouse Unigene: 302123 Human Unigene: 116687 Mouse Unigene: 67419 Rat |