| 產(chǎn)品編號(hào) | bs-13834R |
| 英文名稱 | Rabbit Anti-CENPI antibody |
| 中文名稱 | 著絲粒蛋白I抗體 |
| 別 名 | CENP I; CENPI_HUMAN; centromere protein I; Follicle simulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; FSH primary response, rat, homolog of, 1; FSHP1; FSHPRH1; interphase centromere complex protein 19; Leucine rich primary response gene 1; Leucine rich primary response protein 1; LRPR1; Mis6. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 87kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CENPI: 201-300/756 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. [provided by RefSeq, Jul 2008] Function: CENPI is a constitutive protein of the knetochore that shares limited similarity with Mis6 of S. pombe. The kinetochore is a macromolecular complex located at the centromere of chromosomes and provides essential functions for chromosome segregration. CENPI is required for the localization of CENPF and the checkpoint proteins MAD1 and MAD2 to the kinetochore. Subcellular Location: Cytoplasmic and Nuclear Post-translational modifications: Sumoylated. Sumoylated form can be polyubiquitinated by RNF4, leading to its degradation. Desumoylation by SENP6 prevents its degradation. Similarity: Belongs to the mis6 family. SWISS: Q92674 Gene ID: 2491 Database links: Entrez Gene: 2491 Human Omim: 300065 Human SwissProt: Q92674 Human Unigene: 348920 Human |
