產(chǎn)品編號 | bs-16441R |
英文名稱 | Rabbit Anti-ZNF827 antibody |
中文名稱 | 鋅指蛋白827抗體 |
別 名 | Zfp827; Zinc finger protein 827; ZN827_HUMAN; ZNF827. |
研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 119kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF827: 1-100/1081 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ZNF827 (zinc finger protein 827) is a 1,081 amino acid nuclear protein that contains nine C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. Existing as three alternatively spliced isoforms, ZNF827 may be involved in transcriptional regulation. The gene that encodes ZNF827 consists of around 181,000 bases and maps to human chromosome 4q31.2. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 9 C2H2-type zinc fingers. SWISS: Q17R98 Gene ID: 152485 Database links: Entrez Gene: 152485 Human Entrez Gene: 622675 Mouse SwissProt: Q17R98 Human SwissProt: Q505G8 Mouse Unigene: 133916 Human Unigene: 48724 Mouse |