| 產(chǎn)品編號 | bs-18641R |
| 英文名稱 | Rabbit Anti-MAMDC2 antibody |
| 中文名稱 | MAMDC2蛋白抗體 |
| 別 名 | MAM domain-containing protein 2; MAM domain-containing proteoglycan; MAMC2_HUMAN; Mamcan; Mamdc2. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 75kDa |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAMDC2: 601-686/686 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
MAMDC2 is a 686 amino acid secreted protein that localizes to extracellular matrix. Containing four MAM domains and existing as two alternatively spliced isoforms, MAMDC2 is encoded by a gene located on human chromosome 9q21.11. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, Familial dysautonomia and certain leukemias are also associated with chromosome 9. Subcellular Location: Secreted > extracellular space > extracellular matrix. Post-translational modifications: O-glycosylated. Similarity: Contains 4 MAM domains. SWISS: Q7Z304 Gene ID: 256691 Database links: Entrez Gene: 256691 Human Omim: 612879 Human SwissProt: Q7Z304 Human Unigene: 547172 Human |
