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首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-phospho-NMDAR2B (Tyr1472)  antibody (bs-19293R)  
~~~促銷(xiāo),代碼KT202502A~~~
~~~促銷(xiāo),代碼KT202502B~~~
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說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-19293R
英文名稱(chēng) Rabbit Anti-phospho-NMDAR2B (Tyr1472)  antibody
中文名稱(chēng) 磷酸化谷氨酸受體2B抗體
別    名 NMDAR2B (phospho Y1472); p-NMDAR2B (phospho Y1472); AW490526; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-2; Glutamate Receptor Ionotropic N Methyl D Aspartate 2B; Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B; Glutamate receptor ionotropic NMDA2B; Glutamate receptor subunit epsilon 2; Glutamate receptor, ionotropic, NMDA2B (epsilon 2); GRIN 2B; GRIN2B; hNR 3; hNR3; MGC142178; MGC142180; N methyl D asparate receptor channel subunit epsilon 2; N methyl D aspartate receptor subtype 2B; N methyl D aspartate receptor subunit 2B; N methyl D aspartate receptor subunit 3; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDA NR2B; NMDA R2B; Nmdar2b; NMDE2; NMDE2_HUMAN; NME2; NR2B; NR3.   
Specific References  (2)     |     bs-19293R has been referenced in 2 publications.
[IF=6.656] Panwen Liu. et al. Inhibition of GluN2B pathway is involved in the neuroprotective effect of silibinin on streptozotocin-induced Alzheimer's disease models. PHYTOMEDICINE. 2022 Dec;:154594  WB ;  Rat, Mouse.  
[IF=3.234] Liang X et al. Panaxadiol inhibits synaptic dysfunction in Alzheimer's disease and targets the Fyn protein in APP/PS1 mice and APP-SH-SY5Y cells. Life Sci. 2019 Mar 15;221:35-46.  ICC&WB ;  Human.  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 180kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1472: HV(p-Y)EK 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 subunit of the NMDA receptor glutamate gated ion channel; displays voltage dependent sensitivity to magnesium, calcium permeability, and glycine regulated activity; may facilitate learning and long term potentiation [RGD, Feb 2006]

Function:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Subcellular Location:
Cell membrane. Cell junction, synapse, postsynaptic cell membrane.

Tissue Specificity:
Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.

Similarity:
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.

SWISS:
Q13224

Gene ID:
2904

Database links:

Entrez Gene: 2904 Human

Entrez Gene: 14812 Mouse

Entrez Gene: 24410 Rat

Omim: 138252 Human

SwissProt: Q13224 Human

SwissProt: Q01097 Mouse

SwissProt: Q00960 Rat

Unigene: 654430 Human

Unigene: 436649 Mouse

Unigene: 9711 Rat



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