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Rabbit Anti-PCDH19  antibody (bs-19911R)  
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產品編號 bs-19911R
英文名稱 Rabbit Anti-PCDH19  antibody
中文名稱 原鈣粘附蛋白19抗體
別    名 KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19.  
研究領域 細胞生物  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 124kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDH19: 151-250/1148 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

Function:
Potential calcium-dependent cell-adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.

DISEASE:
Epileptic encephalopathy, early infantile, 9

Similarity:
Contains 6 cadherin domains.

SWISS:
Q8TAB3

Gene ID:
57526

Database links:

Entrez Gene: 57526 Human

Entrez Gene: 101125719 Gorilla

Entrez Gene: 100059478 Horse

Entrez Gene: 279653 Mouse

Omim: 300460 Human

SwissProt: Q8TAB3 Human

SwissProt: Q80TF3 Mouse

Unigene: 4993 Human

Unigene: 39738 Mouse



產品圖片
Sample: 293T Cell (Human) Lysate at 30 ug Primary: Anti- PCDH19 (bs-19911R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 124 kD Observed band size: 124 kD
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