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Rabbit Anti-PLD3  antibody (bs-12717R)  
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產品編號 bs-12717R
英文名稱 Rabbit Anti-PLD3  antibody
中文名稱 膽堿磷酸酯酶3抗體
別    名 Choline phosphatase 3; HindIII K4L homolog; HU K4; Hu-K4; HUK4; Phosphatidylcholine hydrolyzing phospholipase D3; Phosphatidylcholine-hydrolyzing phospholipase D3; Phospholipase D family, member 3; Phospholipase D3; PLD 3; PLD3; PLD3_HUMAN.  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLD3: 201-300/490 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Widely expressed. Expressed at higher level in brain. Expressed at low level in corpus callosum, suggesting that it is highly expressed in neurons.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the phospholipase D family.
Contains 2 PLD phosphodiesterase domains.

SWISS:
Q8IV08

Gene ID:
23646

Database links:

Entrez Gene: 23646 Human

Entrez Gene: 18807 Mouse

Entrez Gene: 361527 Rat

SwissProt: Q2KJJ8 Cow

SwissProt: Q8IV08 Human

SwissProt: O35405 Mouse

SwissProt: Q5FVH2 Rat

Unigene: 257008 Human

Unigene: 6483 Mouse

Unigene: 128036 Rat



產品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-LD3? (bs-12717R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
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