| 產(chǎn)品編號 | C05-03030 |
| 英文名稱 | 1M Dithiothreitol (DTT) |
| 中文名稱 | 1M DTT溶液/二硫蘇糖醇 |
| 別 名 | (2S,3S)-1,4-Bis(sulfanyl)butane-2,3-diol; (2S,3S)-1,4-Dimercaptobutane-2,3-diol; D-threo-1,4-Dimercaptobutane-2,3-diol; D-threo-1,4-Dimercapto-2,3-butanediol; 1,4-Dithio-D-threitol; Cleland's reagent; Reductacryl; 1M DTT; |
| 保存條件 | Store at -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
DTT is frequently used to reduce the disulfide bonds of proteins and, more generally, to prevent intramolecular and intermolecular disulfide bonds from forming between cysteine residues of proteins. DTT is oftentimes used along with sodium dodecylsulfate in SDS-PAGE to further denature proteins by reducing their disulfide bonds to allow for better separation of proteins during electrophoresis. DTT is used as a reducing or "deprotecting" agent for thiolated DNA. The terminal sulfur atoms of thiolated DNA have a tendency to form dimers in solution, especially in the presence of oxygen. |
