| 產(chǎn)品編號 | C07-01004 |
| 英文名稱 | Ac-IETD-pNA |
| 中文名稱 | Caspase 8顯色底物 (Ac-IETD-pNA) |
| 別 名 | N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide; Caspase-8 Substrate; N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase-8 Substrate(Chromogenic); N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase Substrate, chromogenic; Ac-IETD-pNA (Caspase 8顯色底物); Caspase 8顯色底物,Ac-IETD-pNA; |
| 保存條件 | Store at -20 °C for one year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Chromogenic substrate for caspase 8 and granzyme B. IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3. 純度：>95%(HPLC) 分子式：C34H37N9O11 分子量：747.7 序列：N-Acetyl-Ile-Glu-Thr-Asp-p-Nitroanilide 來源：合成 外觀/性狀：Lyophilized Yellow Powder 溶解性：Soluble in DMSO 敏感性：對光敏感 簡介：Ac-IETD-pNA是Caspase 8的底物，被剪切后可產(chǎn)生黃色的pNA (p-nitroaniline)，pNA在405nm附近有強(qiáng)吸收，可以通過測定吸光度來檢測Caspase 8的活性。 用途：Chromogenic substrate for caspase-1, -4 and -5. Most potent for caspase-1. ; max of pNA 400nm. 配方：20mM in DMSO: 5mg加入0.39ml DMSO，或每12.77mg加入1ml DMSO，配制成20mM溶液。 |
