產(chǎn)品編號 | C07-01005 |
英文名稱 | Ac-YVAD-pNA |
中文名稱 | Caspase 1顯色底物 (Ac-YVAD-pNA) |
別 名 | N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide; Caspase Substrate, chromogenic; Caspase 1 substrate (chromogenic); Caspase-1 Substrate; N-Acetyl-Tyr-Val-Ala-Asp-p-Nitroanilide; Ac-YVAD-pNA (Caspase 1顯色底物) |
保存條件 | Store at -20 °C for one year. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.
級別/純度:BR, ≥95% (HPLC) CSA:149231-66-3 分子式:C29H36N6O10 分子量:268.63 序列:N-Acetyl-Tyr-Val-Ala-Asp-p-Nitroanilide 來源:合成 溶解性:Soluble in DMSO 敏感性:對光敏感 簡介:Ac-YVAD-pNA是Caspase 1的底物,被剪切后可產(chǎn)生黃色的pNA (p-nitroaniline),pNA在405nm附近有強吸收,可以通過測定吸光度來檢測Caspase 1的活性。 用途:用作半胱氨酸的天冬氨酸蛋白水解酶顯色底物。 配方:5mg加入0.4ml DMSO,或每12.57mg加入1ml DMSO,配制成20mM溶液。20mM包裝用DMSO配制。 |