產(chǎn)品編號(hào) | C07-01007 |
英文名稱 | Ac-LEHD-pNA |
中文名稱 | Caspase 9顯色底物 (Ac-LEHD-pNa) |
別 名 | Ac-Leu-Glu-His-Asp-pNA; Caspase-9 substrate (chromogenic); N-Acetyl-Leu-Glu-His-Asp-p-Nitroanilide; Caspase-9 Substrate; N-Acetyl-Leu-Glu-His-Asp-pNA; Caspase 9 Substrate, chromogenic; Ac-LEHD-pNA (Caspase 9顯色底物); Caspase 9顯色底物, Ac-LEHD-pNA; |
保存條件 | Store at -20 °C for one month or -80℃ for 6 months. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Caspase 9 is an initiator caspase that cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide).
純度:>95%(HPLC) 分子式:C29H38N8O11 分子量:674.66 序列:N-Acetyl-Leu-Glu-His-Asp-p-Nitroanilide 來源:合成 外觀/性狀:Lyophilized Yellow Powder 溶解性:Soluble in DMSO 敏感性:對光敏感 簡介:caspase 9是一種啟動(dòng)子caspase,它能切割前蛋白酶3和前蛋白酶7來促進(jìn)凋亡級(jí)聯(lián)。Ac-LEHD-pNA是Caspase 9的底物,被剪切后可產(chǎn)生黃色的pNA (p-nitroaniline),pNA在405nm附近有強(qiáng)吸收,可以通過測定吸光度來檢測Caspase 9的活性。 用途:用作半胱氨酸的天冬氨酸蛋白水解酶顯色底物。 配方:20mM in DMSO: 5mg加入0.37ml DMSO,或每13.49mg加入1ml DMSO,配制成20mM溶液。 |