產(chǎn)品編號(hào) | bsm-54769R |
英文名稱 | TGN46 Recombinant Rabbit mAb |
中文名稱 | 高爾基體網(wǎng)絡(luò)整合膜蛋白重組兔單抗 |
別 名 | TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 1; Trans-Golgi network integral membrane protein 2; Trans-Golgi network protein TGN51; TTGN2. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 18D19 |
交叉反應(yīng) | Human (predicted: Mouse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TGN46 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] Function: May be involved in regulating membrane traffic to and from trans-Golgi network. Subcellular Location: Cell membrane. Golgi apparatus > trans-Golgi network membrane. Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes. Tissue Specificity: Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. SWISS: O43493 Gene ID: 10618 Database links: Entrez Gene: 10618 Human Omim: 603062 Human SwissProt: O43493 Human Unigene: 593382 Human Unigene: 11349 Rat |
產(chǎn)品圖片 |
Sample:
Lane 1: Human MCF-7 cell lysates
Lane 2: Human MDA-MB-231 cell lysates
Lane 3: Human HeLa cell lysates
Lane 4: Human HepG2 cell lysates
Lane 5: Human U251 cell lysates
Lane 6: Human A549 cell lysates
Primary: Anti-TGN46 (bsm-54769R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: kDa
Observed band size: 95 kDa
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