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Human HE4 (V7503)  
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產品編號 V7503
英文名稱 Human HE4
中文名稱 附睪分泌蛋白4單克隆抗體
別    名 WFDC2 WAP four-disulfide core domain 2; dJ461P17.6; EDDM4; epididymal protein 4; Epididymal secretory protein E4; Epididymis specific whey acidic protein type four disulfide core; HE 4; Major epididymis specific protein E4; Major epididymis-specific protein E4; MGC57529; Putative protease inhibitor WAP5; WAP 5; WAP domain containing protein HE4; WAP four disulfide core domain 2; WAP four disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP5; WFDC 2; WFDC2; WFDC2_HUMAN.  
克 隆 號 5D12
理論分子量 13kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 >1mg/ml
緩 沖 液 0.01M PBS (pH7.4).
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

Function:
Broad range protease inhibitor.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

Similarity:
Contains 2 WAP domains.

SWISS:
Q14508

Gene ID:
10406

Database links:

Entrez Gene: 10406 Human

SwissProt: Q14508 Human

Unigene: 2719 Human



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