產(chǎn)品編號(hào) | bsm-54700R |
英文名稱 | WRN Recombinant Rabbit mAb |
中文名稱 | WRN重組兔單克隆抗體 |
別 名 | DKFZp686C2056; DNA helicase; DNA helicase, RecQ like type 3; Exonuclease WRN; RecQ protein-like 2; RecQ-like type 3; RecQ3; RECQL2; RECQL3; Werner syndrome ATP-dependent helicase; Werner syndrome helicase; Werner syndrome protein; Werner syndrome, RecQ helicase like; WRN; Bifunctional 3'-5' exonuclease/ATP-dependent helicase WR; WRN_HUMAN . |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 7H2 |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | WB=1:200-1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 162 kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant Human WRN protein |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017] Gene ID: 7486 |