| 產(chǎn)品編號(hào) | D51640 |
| 英文名稱(chēng) | Azeliragon HCl |
| 中文名稱(chēng) | |
| 別 名 | RAGE抑制劑 |
| 克 隆 號(hào) | |
| CAS | 1284150-65-7 |
| 理論分子量 | 605.04 kDa |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Azeliragon free base, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy. |
