| 產(chǎn)品編號(hào) | D62052 |
| 英文名稱 | Gefapixant |
| 中文名稱 | |
| 別 名 | MK-7264; AF219; RO 4926219 |
| 克 隆 號(hào) | |
| CAS | 1015787-98-0 |
| 理論分子量 | 353.4 kDa |
| 保存條件 | -20℃ |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis |
