| 產(chǎn)品編號(hào) | D58195 |
| 英文名稱 | BRD6989 |
| 中文名稱 | |
| 克 隆 號(hào) | |
| CAS | 642008-81-9 |
| 理論分子量 | 264.33 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. |