| 產(chǎn)品編號 | bsm-63112R |
| 英文名稱 | phospho-NBN (S343) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化DNA修復(fù)蛋白NBS1重組兔單抗 |
| 別 名 | Cell cycle regulatory protein P95; NBN; NBS; NIBRIN; NIJMEGEN BREAKAGE syndrome protein 1; p95-NBS1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 9F2 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 85 kDa |
| 檢測分子量 | 95 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human p95 NBS1 around the phosphorylation site of S343: SL-pS-QG |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. SWISS: O60934 Gene ID: 4683 NBS1蛋白可與Mre11和Rad50蛋白形成一個Mre11-Rad50-NBS1復(fù)合物,在DNA的復(fù)制和DNA雙鏈斷裂的修復(fù)等過程中起重要作用。 |
