| 產(chǎn)品編號(hào) | bsm-63189R |
| 英文名稱 | phospho-GSK3 beta (S9) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化糖原合酶激酶-3β重組兔單抗 |
| 別 名 | glycogen synthase kinase 3 beta; GSK-3 beta; GSK3B; GSK3beta isoform. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 61C |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:5000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 47 kDa |
| 檢測(cè)分子量 | 46 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human GSK3 beta around the phosphorylation site of S9: TT-pS-FA |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1.Requires primed phosphorylation of the majority of its substrates. SWISS: P49841 Gene ID: 2932 激酶和磷酸酶（Kinases and Phosphatases） GSK3β是一個(gè)serine/threonine,proline 直接激酶，參與多個(gè)信號(hào)通路的排列，包括糖原合成和細(xì)胞黏附，GSK3β與AD病有關(guān)。此抗體識(shí)別分子量為47kDa 的GSK-3β蛋白。 |
