產(chǎn)品編號(hào) | IHC0395 |
英文名稱(chēng) | BRD4/CAP Ready-To-Use IHC Kit |
中文名稱(chēng) | 染色體相關(guān)蛋白CAP即用型免疫組化試劑盒 |
別 名 | BRD4; CAP; HUNK1; HUNKI; MCAP |
克 隆 號(hào) | |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus. SWISS: O60885 Gene ID: 23476 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse colon tissue slide using IHC0395 (BRD4/CAP IHC Kit).
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