| 產(chǎn)品編號(hào) | bs-2038R-FITC |
| 英文名稱1 | Rabbit Anti-CD34/FITC Conjugated antibody |
| 中文名稱 | FITC標(biāo)記的CD34抗體 |
| 別 名 | CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN; Hematopoietic Stem Cell Marker; Endothelial Markers; Tumor biomarkers. |
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Journal
PMID
IF
Application
[IF=6.03] Shimizu, Takayoshi, et al. "Bioactivity of sol–gel-derived TiO 2 coating on polyetheretherketone: In vitro and in vivo studies." Acta Biomaterialia (2016). Rabbit.
[IF=4.486] Jingyu Liu. et al. Low‐energy shock wave pretreatment recruit circulating endothelial progenitor cells to attenuate renal ischaemia reperfusion injury. J Cell Mol Med. 2020 Sep;24(18):10589-10603 FC ; Rat.
[IF=3.989] Zhang C et al. CXCR4-Overexpressing Umbilical Cord Mesenchymal Stem Cells Enhance Protection against Radiation-Induced Lung Injury. Stem Cells Int. 2019 Feb 5;2019:2457082. FCM ; Human.
[IF=2.2] Gierloff, M., et al. "In vitro comparison of different carrier materials with rat bone marrow MSCs." Clinical Oral Investigations (2013): 1-13. Rat.
[IF=2.07] He, Yangyan, et al. "Sustained Release of Stromal Cell-Derived Factor-1α from Injectable Hydrogels in Combination with Endothelial Progenitor Cells Effectively Promotes Neovascularization in Ischemic Diabetic Rats." Journal of Biomaterials and Tissue Engineering 6.2 (2016): 134-140.
[IF=2.07] Wu, Ziheng, et al. "Enhancement of the Anti-Apoptotic and Angiogenic Properties of Bone Marrow-Derived Endothelial Progenitor Cells by Bcl-2 Gene Transfer in Rats." Journal of Biomaterials and Tissue Engineering 5.11 (2015): 895-903. other ;
[IF=1.55] Wang, Yu, et al. "Irradiation alters the differentiation potential of bone marrow mesenchymal stem cells." Molecular medicine reports (2015). Rat.
[IF=1.48] Zhou, Hao, et al. "Exendin-4 enhances the migration of adipose-derived stem cells to neonatal rat ventricular cardiomyocyte-derived conditioned medium via the phosphoinositide 3-kinase/Akt-stromal cell-derived factor-1α/CXC chemokine receptor 4 pathway." Molecular Medicine Reports. Rat.
[IF=1.15] Zhang, Ying, et al. "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." In Vitro Cellular & Developmental Biology-Animal (2016): 1-9. FCM ; Rat.
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| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 細(xì)胞表面分子 糖蛋白 細(xì)胞類型標(biāo)志物 血管內(nèi)皮細(xì)胞 自然殺傷細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD34 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. Hematopoietic Stem Cell Marker Endothelial Markers Tumor biomarkers Function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Post-translational modifications: Highly glycosylated. Phosphorylated on serine residues by PKC. Similarity: Belongs to the CD34 family. Database links: Entrez Gene: 947 Human Omim: 142230 Human SwissProt: P28906 Human Unigene: 374990 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 造血干細(xì)胞標(biāo)志物 內(nèi)皮標(biāo)志物 腫瘤生物標(biāo)志物 細(xì)胞表面的唾液粘蛋白。 |
