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Rabbit Anti-DUOXA1/Gold Conjugated antibody (bs-11433R-Gold)
訂購熱線:400-901-9800
訂購郵箱:[email protected]
訂購QQ:  400-901-9800
技術支持:[email protected]
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11433R-Gold
英文名稱1 Rabbit Anti-DUOXA1/Gold Conjugated antibody
中文名稱 膠體金標記的雙氧化酶成熟因子抗體
別    名 DOXA1_HUMAN; Dual oxidase activator 1; Dual oxidase maturation factor 1; duoxa1; NIP; Numb interacting protein; Numb-interacting protein; NUMBIP.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  神經(jīng)生物學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DUOXA1 (101-200aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Function:
May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1.

Subunit:
May interact with NUMB.

Subcellular Location:
Membrane; Multi-pass membrane protein

Tissue Specificity:
Specifically expressed in thyroid gland. Also detected in esophagus.

Similarity:
Belongs to the DUOXA family.

Database links:
UniProtKB/Swiss-Prot: Q1HG43.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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