| 產(chǎn)品編號 | bs-16911R-AP |
| 英文名稱 | Rabbit Anti-KCNN2/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的電導(dǎo)鈣激活鉀通道蛋白2抗體 |
| 別 名 | Apamin sensitive small conductance Ca2+ activated potassium; Apamin sensitive small conductance Ca2+ activated potassium channel; hSK2; KCa2.2; Kcnn2; KCNN2_HUMAN; Potassium intermediate/small conductance calcium activated; Potassium intermediate/small conductance calcium activated channel subfamily N member 2; SK2; SKCa 2; SKCa2; Small conductance calcium activated potassium channel; Small conductance calcium activated potassium channel protein 2; Small conductance calcium-activated potassium channel protein 2. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 64kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNN2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Subcellular Location: Membrane. Tissue Specificity: Widely expressed. Similarity: Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily. Database links: Entrez Gene: 3781 Human Entrez Gene: 395579 Chicken Entrez Gene: 140492 Mouse Omim: 605879 Human SwissProt: Q6PJI0 Human SwissProt: Q9H2S1 Human SwissProt: P58390 Mouse SwissProt: Q3UF29 Mouse SwissProt: Q540U9 Mouse SwissProt: Q80X11 Mouse SwissProt: Q8C7F3 Mouse SwissProt: Q8CAD4 Mouse SwissProt: Q8CCH4 Mouse Unigene: 98280 Human Unigene: 458654 Mouse Unigene: 44421 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
