| 產(chǎn)品編號(hào) | bs-19019R-Gold |
| 英文名稱 | Rabbit Anti-NARFL/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的NARFL蛋白抗體 |
| 別 名 | Cytosolic Fe-S cluster assembly factor NARFL; FLJ21988; HPRN; IOP1; Iron only hydrogenase like protein 1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; Nuclear prelamin A recognition factor like; Nuclear prelamin A recognition factor like protein; nuclear prelamin A recognition factor-like protein; PRN; Protein related to Narf; uclear prelamin A recognition factor-like. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NARFL |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: NARFL (nuclear prelamin A recognition factor-like), also known as cytosolic Fe-S cluster assembly factor NARFL, HPRN, PRN (protein related to Narf), LET1L or IOP1 (iron-only hydrogenase-like protein 1), is a 476 amino acid protein belonging to the NARF family. Widely expressed, NARFL is required for extramitochondrial sulfur and iron protein maturation and may indirectly negatively regulate HIF-1?expression. Existing as three alternatively spliced isoforms, NARFL is encoded by a gene that maps to human chromosome 16p13.3 and murine chromosome 17 A3.3. Function: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. Subcellular Location: Nuclear Cytosolic iron-sulfur protein assembly complex. Tissue Specificity: Widely expressed. Similarity: Belongs to the NARF family. Database links: Entrez Gene: 64428 Human Omim: 611118 Human SwissProt: Q9H6Q4 Human Unigene: 513247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
